Upcoming Event: Oden Institute Seminar

Mathematical modeling of human brain transport: from medical images to biophysical simulation

Marie Rognes, Chief Research Scientist/Research Professor, Department for Numerical Analysis and Scientific Computing, Simula Research Laboratory, Oslo, Norway

Abstract

Your brain has its own waterscape: whether you are reading, thinking or sleeping, fluid flows through or around the brain tissue, clearing waste in the process. These biophysical processes are crucial for the well-being and function of the brain. In spite of their importance we understand them but little, and mathematical and computational modelling could play a crucial role in gaining new insight. In this talk, I will give an overview of mathematical, mechanical and numerical approaches to understand mechanisms underlying solute transport in the human brain. Topics include uncertainty quantification and optimal control, fluid-structure interactions, and mixed finite element discretizations and preconditioning.

email: meg@simula.no
url: www.simula.no/people/meg
https://orcid.org/0000-0002-6872-3710

Biography

Marie E. Rognes is Research Professor in Scientific Computing and Numerical Analysis at Simula Research Laboratory, Oslo, Norway and is currently a Visiting Scholar at the University of California San Diego in La Jolla. She joined Simula Research Laboratory in 2009, after received her Ph.D from the University of Oslo in the same year, led its Department for Biomedical Computing from 2012-2016, and currently leads a number of research projects focusing on mathematical modeling and numerical methods for brain mechanics including an ERC Starting Grant in Mathematics (2017-2023). She won the 2015 Wilkinson Prize for Numerical Software, the 2018 Royal Norwegian Society of Sciences and Letters Prize for Young Researchers within the Natural Sciences, is a member of the Norwegian Academy of Technological Sciences, and a member of the FEniCS Steering Council.