To study mitral valve disease and repair, researchers in the Willerson Center for Cardiovascular Modeling and Simulation developed a novel, completely noninvasive computational method to estimate mitral valve leaflet in‐plane strains from clinical‐quality, realtime three‐dimensional echocardiography images. Their work was featured on the cover of the December 2018 Numerical Methods in Biomedical Engineering journal.
Assessment of mitral valve function is important in many diagnostic, prognostic, and surgical planning applications for treatment of mitral valve disease. Yet, to date, there are no accepted noninvasive methods for determination of the valve's leaflet deformation, which is a critical metric of its function.
Bruno V. Rego, Amir Khalighi, and Andrew Drach in the Willerson Center for Cardiovascular Modeling and Simulation directed by ICES Professor Michael S. Sacks, were lead authors. Other researchers included Erik Lai, Alison Pouch, Robert Gorman and Joseph Gorman III of the Gorman Cardiovascular Research Group at the University of Pennsylvania School of Medicine, as well as Michael Sacks.