Past Event: Oden Institute Seminar

Probing lipid bilayer mobility at specific depths using vibrational spectroscopy

Igor Rubstov, Tulane University

Abstract

We developed small size vibrational labels capable of testing membrane mobility via two-dimensional infrared spectroscopy. Despite low polarity of the membrane interior, the vibrational label shows a significant inhomogeneous linewidth, which enables measuring accurately lipid membrane mobilities via time-resolved spectral diffusion technique. Because of its small size, the label can be anchored to a specific depth in a bilayer, assessing its local mobility.